Dr. Pedro Lowenstein and Ph.D. Student Anna Argento Speaking at APS Global Physics Summit
3D nematic organization and topological defects in brain tumors in vivo. Presented by Pedro Lowenstein (University of Michigan) Glioblastomas (GBM) are the most common adult brain tumors, characterized by rapid invasion into the normal brain and therapeutic resistance. We previously demonstrated that GBM tumors exhibit self-organized, nematically aligned, multicellular structures, termed “oncostreams,” that influence tumor invasion and malignancy. Here we show the presence of topological defects in glioma…
