Castro and Lowenstein Lab

Bridging single cells to organs: Mesoscale modules as fundamental units of tissue function Read more here

Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways Read the publication here

Dr. Argento will be joining Stig Ove Bøe’s group at the Oslo University Hospital to research cell and tissue dynamics in cancer. 

BME Ph.D. Defense: Structure and Function of Active Nematic Liquid Crystal Order in Brain Tumors Abstract: Glioblastomas (GBM) are the most common adult brain tumors, characterized by rapid invasion into the normal brain and therapeutic resistance. Our lab previously demonstrated that GBM tumors exhibit self-organized, nematically aligned, multicellular structures, termed “oncostreams,” that influence tumor invasion and malignancy. Oncostreams are regulated by collagen fibers and downregulation…

The link to the registration page is here: https://www.asgct.org/events/2025-advancing-cell-and-gene-therapies-for-cancer/registration.   Program here Join the world’s leading experts in Philadelphia’s vibrant Historic District for Advancing Cell + Gene Therapies for Cancer, the premier event dedicated to breakthroughs in oncolytic viruses, cell and immunotherapies, and combination approaches. This is your opportunity to immerse yourself in the latest science, discuss critical challenges, and forge collaborations that will shape the future…

Before she began her first professorship at the University of Manchester in England, Dr. Maria Castro had focused most of her work on neurodegenerative disorders, such as Parkinson’s disease. But after meeting different colleagues and exploring other focus areas, brain cancer became a new field of interest. She was quickly immersed in the world of cancer progression and novel therapeutics. “At the time, no one…

The University of Michigan Board of Regents has named Domenico Grasso, PhD ’87, as the University’s interim president, effective immediately. Read more here