Castro and Lowenstein Lab

Wednesday, September 27 at the Michigan! Join us for a pre-film panel discussion at 6:00 PM with Michelle Hastings, Ph.D.; Maria G. Castro, Ph.D.; Christiane Wobus, Ph.D.; Henry Paulson, M.D., Ph.D.; Peter Todd, M.D., Ph.D.; and moderated by Nils G. Walter, Ph.D. Film screening will begin at 7:00 PM. The story of a doctor’s extraordinary work in the Sixties with a group of catatonic patients…

Congratulations Dr. Syed Faisal, Dr. Maria G. Castro and Dr. Pedro R. Lowenstein on your publication “Adenovirus-mediated combined cytotoxic and immune-stimulatory gene therapy using dual-vector Ad-hCMV-TK and Ad-hCMV-Flt3L: translational explorations from rodents to glioma patients” being accepted in Molecular Therapy.

Dr. Haase has accepted a position as a Bioinformatics Scientist in the Integrative Program for Biological and Genome Sciences (IBGS) at The University of North Carolina at Chapel Hill.

Dr. Castro will be Keynote Speaker at the Finnish Brain Tumor Research Association (FIBTRA) Annual Symposium 8/31/2023-9/1/2023 in Kuopio, Finland. The title of Dr. Castro’s presentation is “Epigenetic Remodeling within Glioma Cells Impacts Myelopoiesis and the Response to Immunotherapies: Clinical Implications”.  Click here to register .

Congratulations to Dr. Pedro Lowenstein Dr. Maria G. Castro, Dr. Maria Luisa Varela, Dr. Faisal Syed, and Molly West on publication “A non-randomized, open-label, dose-finding, first-in-human trial of combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma” being accepted in The Lancet Oncology.

Congratulations to Brandon for being one of the co-recipients of this year’s Herman and Dorothy Miller Award for Innovative Immunology Research.

Congratulations to Ford for being accepted into graduate school in the Translational Neuroscience Program at Wayne State University.

Congratulations to Santiago Haase, Kaushik Banerjee, Brandon McClellan, Ziwen Zhu, Yingxiang Li, Marta Edwards, Pedro Lowenstein and Maria G. Castro for their publication “H3.3-G34R Mutation-Mediated Epigenetic Reprograming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas” in BioRxiv.

Dr. Maria G. Castro for her publication being accepted in BioRxiv. “Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.”

Dr. Castro will be a keynote speaker at the British Neuro-Oncology Society Annual Meeting July 5th-July 7th, 2023, in Manchester. Dr. Castro will be speaking on “Epigenetic reprogramming of the tumor microenvironment leads to enhanced DNA damage response and inhibition of immunosuppressive mechanisms in mutant IDH1 gliomas: clinical implications”. To register for conference, please click here.